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Equimolar Minimum Essential Mixtures (E-MEM) alleviate OHDA mediated hypoactivity. Panel (A) Five cannabinoids (CBs) were used to create the 10 possible three component equimolar mixtures. Panels (B,C) Each of the 500 nM E-MEM (166.7 nM of each cannabinoid) was assessed for its ability modify total distance travelled of (B) Carrier Control (CC) or (C) 150 µM OHDA. Data is normalized to either CC (B) or OHDA (C) (100%). MEM + OHDA vs. OHDA, * = p < 0.05, **p < 0.01.
