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. Author manuscript; available in PMC: 2022 Oct 21.
Published in final edited form as: Nat Aging. 2022 Jul 15;2(7):644–661. doi: 10.1038/s43587-022-00248-2

Extended Data Fig. 4. Additional reliability data on PC clocks in blood.

Extended Data Fig. 4.

a, Reliability of GrimAge and PCGrimAge components calculated using 36 pairs of technical replicates (GSE55763). Data are presented as ICC estimates with 95% confidence interval. b, Reliability of epigenetic age and age acceleration in an independent blood DNAm dataset with 37 pairs of technical replicates (Elysium Dataset 1). Data are presented as ICC estimates with 95% confidence interval. c, PC clocks allow for correction for systemic offsets in epigenetic age across batches. Epigenetic age acceleration is shown for 8 individuals with 18 measurements (across 3 batches, 2 scans, and 3 replicates per batch) in Elysium Dataset 2.