Table 4. Hospitalizations and deaths, regression coefficient and trend of hospitalizations and mortality from drug intoxication by region, Brazil, 2009–2018.

		N	Coefficient	95%CI	p	Estimated date
		Hospitalization
MRx (by region)
	North	3,868	−0.268	−0.586; 0.050	0.087	Stationary
	Central-West Region	7,064	−0.224	−0.407; −0.041	0.023	Decreasing
	Northeast	14,375	−0.080	−0.146; −0.014	0.024	Decreasing
	Southeast	41,522	0.124	−0.020; 0.268	0.082	Stationary
	South	16,446	0.514	0.328; 0.700	0.000	Upwardly
	Brazil	83,275	0.049	−0.072; 0.169	0.371	Stationary
MIP (by region)
	North	142	−0.002	−0.0153; 0.010	0.605	Stationary
	Central-West Region	317	−0.014	−0.026; −0.002	0.025	Decreasing
	Northeast	545	−0.010	−0.011; −0.009	0.000	Decreasing
	Southeast	977	−0.000	−0.003; 0.002	0.705	Stationary
	South	555	0.004	−0.000; 0.009	0.052	Stationary
	Brazil	2,536	−0.004	−0.005; −0.002	0.001	Decreasing
Fatalities
MRx (by region)
	North	108	0.283	−5.478; 6.045	0.911	Stationary
	Central-West Region	172	−3.446	−9.001; 2.109	0.186	Stationary
	Northeast	621	1.772	−1.879; 5.423	0.289	Stationary
	Southeast	1,278	6.680	3.959; 9.401	0.001	Upwardly
	South	416	15.527	6.757; 24.297	0.004	Upwardly
	Brazil	2,595	5.885	3.635; 8.136	0.000	Upwardly
MIP (by region)
	North	108	0.283	−5.478; 6.045	0.911	Stationary
	Central-West Region	172	−3.446	−9.001; 2.109	0.186	Stationary
	Northeast	621	1.772	−1.879; 5.423	0.289	Stationary
	Southeast	1,278	6.680	3.959; 9.401	0.001	Upwardly
	South	416	15.527	6.757; 24.297	0.004	Upwardly
	Brazil	2,595	5.885	3.635; 8.136	0.000	Upwardly

MIP: over-the-counter medications; MRx: prescription drugs.