Figure 5.

Future directions of network-guided neuromodulation for epilepsy. (A) Seizures begin in the SOZ and propagate to a wider seizure network. Neurostimulation at stimulation targets prevent or limit the spread of seizure activity from the SOZ to the wider network. Panels B, C and D ask forward-thinking questions in network-guided neuromodulation epilepsy and draw on recent key studies.^{26,84,118,163,169–171,175–177}