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. 2022 Jun 2;145(10):3522–3535. doi: 10.1093/brain/awac203

Table 2.

Lateralized sensory and motor performance and MRI measures

Dominant hand/hemisphere Non-dominant hand/hemisphere
HC (n = 28) CL− (n = 28) CL+ (n = 22) All patients (n = 50) HC (n = 28) CL− (n = 25) CL+ (n = 25) All patients (n = 50)
Sensory and motor tests
9-HPT, mean (SD) 16.7 (2.01) 20.3 (4.77) a 22.1 (6.01) a 21.1 (5.37) 17.9 (2.01) 19.5 (3.14) a 27.2 (9.21) a,b 23.4 (7.84)
JTHFT, mean (SD) 38.4 (6.30) 48.2 (11.4) a 52.6 (14.9) a 50.1 (13.1) 60.6 (11.5) 71.1 (14.1) a 89.5 (23.0) a,b 80.3 (21.1)
Finger tapping, mean (SD) 48.3 (4.84) 45.0 (8.06) 42.2 (7.92) 43.7 (8.04) 43.8 (5.09) 42.4 (5.15) 34.9 (9.13) a,b 38.6 (8.25)
Sensory deficit score, mean (SD) 0.03 (0.12) 0.79 (0.92) a 0.91 (1.08) a 0.85 (0.99) 0.01 (0.038) 0.53 (0.71) a 1.15 (1.04) a,b 0.845 (0.940)
 Missing, n (%) 0 1 (3.6%) 0 1 (2%) 0 1 (4%) 0 1 (2%)
GODT, mean (SD) 2.90 (0.788) 3.23 (1.02) 3.80 (0.886) a 3.47 (0.996) 2.67 (0.811) 2.84 (0.988) 3.95 (0.563) a,b 3.38 (0.977)
 Missing, n (%) 0 0 1 (4.5%) 1 (2%) 0 1 (4%) 2 (8%) 3 (6%)
MRI measures
CST WM lesion fraction, % mean (SD) 0.942 (1.86) 1.28 (1.92) 1.09 (1.87) 0.703 (1.46) 1.32 (2.43) 1.01 (2.01)
 % median [min, max] 0.102 [0, 7.64] 0.554 [0, 8.13] 0.288 [0, 8.13] 0.223 [0, 5.53] 0.711 [0, 11.6] 0.287 [0, 11.6]
Pericentral CTh, mm, mean (SD) 2.60 (0.088) 2.55 (0.105) 2.50 (0.111) a 2.53 (0.109) 2.55 (0.0862) 2.54 (0.092) 2.46 (0.126) a,b 2.50 (0.116)

9-HPT = 9-hole peg test; CL− = patients with no cortical lesion in the contralateral handknob region of interest; CL+ = patients with one or more cortical lesions in the contralateral handknob region of interest; CTh = cortical thickness; GODT = grating orientation discrimination task; HC = healthy control; JTHFT = Jebsen Taylor hand function test; SD = standard deviation; WM = white matter.

Significant values are highlighted in bold.

a

P < 0.05 between healthy controls and patient group.

b

P < 0.05 between CL− and CL+.