Table 2.
Dominant hand/hemisphere | Non-dominant hand/hemisphere | |||||||
---|---|---|---|---|---|---|---|---|
HC (n = 28) | CL− (n = 28) | CL+ (n = 22) | All patients (n = 50) | HC (n = 28) | CL− (n = 25) | CL+ (n = 25) | All patients (n = 50) | |
Sensory and motor tests | ||||||||
9-HPT, mean (SD) | 16.7 (2.01) | 20.3 (4.77) a | 22.1 (6.01) a | 21.1 (5.37) | 17.9 (2.01) | 19.5 (3.14) a | 27.2 (9.21) a,b | 23.4 (7.84) |
JTHFT, mean (SD) | 38.4 (6.30) | 48.2 (11.4) a | 52.6 (14.9) a | 50.1 (13.1) | 60.6 (11.5) | 71.1 (14.1) a | 89.5 (23.0) a,b | 80.3 (21.1) |
Finger tapping, mean (SD) | 48.3 (4.84) | 45.0 (8.06) | 42.2 (7.92) | 43.7 (8.04) | 43.8 (5.09) | 42.4 (5.15) | 34.9 (9.13) a,b | 38.6 (8.25) |
Sensory deficit score, mean (SD) | 0.03 (0.12) | 0.79 (0.92) a | 0.91 (1.08) a | 0.85 (0.99) | 0.01 (0.038) | 0.53 (0.71) a | 1.15 (1.04) a,b | 0.845 (0.940) |
Missing, n (%) | 0 | 1 (3.6%) | 0 | 1 (2%) | 0 | 1 (4%) | 0 | 1 (2%) |
GODT, mean (SD) | 2.90 (0.788) | 3.23 (1.02) | 3.80 (0.886) a | 3.47 (0.996) | 2.67 (0.811) | 2.84 (0.988) | 3.95 (0.563) a,b | 3.38 (0.977) |
Missing, n (%) | 0 | 0 | 1 (4.5%) | 1 (2%) | 0 | 1 (4%) | 2 (8%) | 3 (6%) |
MRI measures | ||||||||
CST WM lesion fraction, % mean (SD) | — | 0.942 (1.86) | 1.28 (1.92) | 1.09 (1.87) | — | 0.703 (1.46) | 1.32 (2.43) | 1.01 (2.01) |
% median [min, max] | — | 0.102 [0, 7.64] | 0.554 [0, 8.13] | 0.288 [0, 8.13] | — | 0.223 [0, 5.53] | 0.711 [0, 11.6] | 0.287 [0, 11.6] |
Pericentral CTh, mm, mean (SD) | 2.60 (0.088) | 2.55 (0.105) | 2.50 (0.111) a | 2.53 (0.109) | 2.55 (0.0862) | 2.54 (0.092) | 2.46 (0.126) a,b | 2.50 (0.116) |
9-HPT = 9-hole peg test; CL− = patients with no cortical lesion in the contralateral handknob region of interest; CL+ = patients with one or more cortical lesions in the contralateral handknob region of interest; CTh = cortical thickness; GODT = grating orientation discrimination task; HC = healthy control; JTHFT = Jebsen Taylor hand function test; SD = standard deviation; WM = white matter.
Significant values are highlighted in bold.
P < 0.05 between healthy controls and patient group.
P < 0.05 between CL− and CL+.