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Effect of AS-IV on pyroptosis of BMDMs. (a) ROS was detected by flow cytometry. (b) The protein levels of NLRP3, cleaved cas-1, cleaved IL-1β, cleaved IL-18 and GSDMD-N were determined by western blot in the BMDMs. (c-g) each band was quantified. data represent three independent experiments. values are expressed as mean ± SD (n = 6 of each group). **P < 0.01 vs the sham group, ##P < 0.01 vs the MI group, #P < 0.05 vs the MI group.
