Table 1.

Summary of Systematic Reviews Examining Venous Thromboembolism Risk in Rheumatoid Arthritis Patients

First Author	Year	Number of Studies	Inclusion Criteria	Main Outcomes
HU et al3	2021	12	Studies evaluating the incidence of VTE, DVT, and PE in RA patients	OR of DVT in RA patients relative to controls: (2.25, 95% CI: 1.70 to 2.98, p<0.001) OR of PE in RA patients relative to controls (2.15, 95% CI: 1.39 to 3.49, p=0.001). OR of VTE in RA patients relative to controls (2.23, 95% CI: 1.79 to 2.77, p<0.001)
Lee and Pope.55	2014	10	Studies evaluating the incidence of VTE, DVT, and PE in RA patients	OR of DVT in RA patients relative to controls: 2.23 (95% CI: 2.02 to 2.47) Cumulative incidence of VTE is 2.18% (95% CI:1.82% to 2.54%)
Ungprasert et al2	2014	9	Observational studies (case-control, cross-sectional, cohort) evaluating the association between RA and VTE, DVT or PE	Pooled risk ratio for VTE 1.96 (95% CI 1.81–2.11) Pooled risk ratio for DVT= 2.08 (95% CI 1.75–2.47) Pooled risk ratio for PE= 2.17 (95% CI 2.05–2.31)

Abbreviations: RA, rheumatoid arthritis; VTE, venous thromboembolism; DVT, deep venous thrombosis; PE, pulmonary embolism; CI, confidence interval; OR, odds ratio.