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. 2022 Oct 14;2022:1052359. doi: 10.1155/2022/1052359

Figure 4.

Figure 4

The effects of SD treatment on the levels of the TLR4/TRAF6/NF-κB and IL-6/ROR-γt/STAT3 pathways' related genes and proteins in the nasal mucosa of AR mice ((n) = 6). (A-E) The levels of TLR4, TRAF6, IL-6, ROR-γt, and STAT3 mRNA were measured by quantitative real-time PCR. (F-M) The levels of TLR4, TRAF6, p-IκBα/IκBα, NF-κB, ROR-γt, and p-STAT3/STAT3 proteins were measured by using the western blot. All error bars represent the mean ± standard deviation. ##P < 0.01, compared to the control group; ∗P < 0.05, ∗∗P < 0.01, compared to the AR group. SD: Saposhnikovia divaricata, AR: allergic rhinitis, TLR4: toll-like receptors 4, TRAF6: TNF receptor-associated factor 6, IL-6: interleukins-6, IκBα: inhibitor of NF-κb, ROR-γt: retinoid-related orphan nuclear receptor γt, and STAT3: signal transducer and activator of transcription 3.