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. 2022 Oct 14;2022:9494910. doi: 10.1155/2022/9494910

Figure 1.

Figure 1

miR-3613-5p is upregulated in drug-resistant tissue and breast cancer cells. (a) The expression level of miR-3613-5p in GEO chip (GSE73736) of drug-sensitive tissue and drug-resistant tissue. ∗p < 0.05, n = 10. (b) Cell viability of doxorubicin nonresistant and resistant breast cancer cell lines (MCF-7 and MDA-MB-231, MCF-7/DOX, and MDA-MB-231/DOX, respectively) after different doses of doxorubicin treatments was assessed with CCK8. (c) qRT-PCR was performed to assess the relative levels of miR-3613-5p in MCF-7, MCF-7/DOX, MDA-MB-231, and MDA-MB-231/DOX. ∗∗p < 0.01. Data are mean ± S.D. of 3 independent experiments.