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. Author manuscript; available in PMC: 2022 Oct 22.
Published in final edited form as: Am J Med Genet B Neuropsychiatr Genet. 2017 Jul 10;174(6):651–660. doi: 10.1002/ajmg.b.32567

FIGURE 1.

FIGURE 1

Interplay of nutrition, microbiome, and epigenome. This is a simplified depiction of what happens in the GI tract, and how the outcome in the form of metabolites and byproducts can ultimately affect the epigenetics in other tissues of the body. This change can be the result of direct interaction between these metabolites or secondary to activation of an immune response