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. 2022 Aug 29;3(10):1151–1164. doi: 10.1038/s43018-022-00416-8

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Extended Data Fig. 5 — Coefficient results for the intensity-based PD-L1 intensity features from the 10-fold train–test scheme for the LR IHC-A model. The box-and-whisker plots show the mean and the interquartile range (25–75%) as boxes, the minimum and maximum as whiskers up to 1.5 times the IQR and datapoints outside the IQR range as diamonds, for N = 10 fits. The adjoined bar plot shows the number of times, for a given feature, the following criteria were satisfied: (1) if applicable, the feature was selected as part of the radiomics filtering process, (2) the magnitude of the feature’s weight was at least 1 standard deviation from zero and (3) the magnitude of the feature’s weight was greater than 0.01. Only coefficients selected more than once are shown, up to 100.

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