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. 2022 Oct 17;3(10):1211–1227. doi: 10.1038/s43018-022-00438-2

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Extended Data Fig. 9 — (a) Characterization of p-ALK antibody in cytospin slides. Data are representative of two repeats with similar results. (b) A peptide competition assay was carried out to characterize p-Y19 CDK9 antibody by IHC staining of tumor tissue from ovarian cancer patient. Different peptides as indicated were used to incubate with p-Y19 CDK9 antibody. Data are representative of two repeats with similar results. (c) Clinical relevance of p-ALK and p-Y19 CDK9 in human ovarian TMA analysis (Biomax,US, #OV809b). (d–f) Representative images (d) and quantification of IHC staining for the correlation between HR factors (RAD51, CtIP, or p-RPA) and p-ALK (e) or p-Y19 CDK9 (f), by human ovarian tissue microarray analysis (Biomax,US, #OV809b). Bar, 20 µm. Statistical analysis was carried out using the two-side Fisher’s exact test. The experiment was performed an additional time with similar results.