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. 2022 Jun;76:None. doi: 10.1016/j.ceb.2022.102085

Table 1.

. A summary of the data available for homologs of the EMC components in two model apicomplexans, Toxoplasma gondii, and Plasmodium falciparum. Fitness scores for Toxoplasma are from the study by Sidik et al. [40], and for Plasmodium falciparum are from a PiggyBac screen [41]. In both, lower score reflects higher contribution to fitness. Localisation prediction is based on localisation of organelle proteins by isotope tagging in Toxoplasma [42]. Presence in a complexome analysis provides evidence for belonging to the same complex [17].

Toxoplasma gondii
Plasmodium falciparum
Gene ID Fitness-conferring score Localisation prediction Gene ID Present in complexome analysis Fitness-conferring score
EMC1 TGME49_205740 −5.03 ER PF3D7_0811200 Yes −3.23
EMC2 TGME49_267840 −4.08 ER PF3D7_1410000 Yes −3.42
EMC3 TGME49_230100 −3.02 ER PF3D7_1360200 Yes −2.81
EMC4 TGME49_259000 −4.77 ER PF3D7_1435400 Yes −3.3
EMC5 TGME49_293200 −2.68 ER PF3D7_0306700 Yes −3.39
EMC6 TGME49_239690 −3.57 No data PF3D7_1214400 No −2.76
EMC7 TGME49_243390 −1.71 ER PF3D7_1310500 Yes −3.08
EMC8 TGME49_249310 −4.1 ER PF3D7_1139900 Yes −2.84