Table 3.
QOL in responders group and non-responders group (n = 100).
| Variables | Responders group (n = 43) | Non responders group (n = 57) | p-value |
|---|---|---|---|
| Age | 32.23 ± 13.00 | 28.40 ± 9.90 | 0.097 |
| Gender | 0.138 | ||
| • Male | 24 (55.81) | 41 (71.93) | |
| • Female | 19 (44.19) | 16 (28.07) | |
| Age at onset of epilepsy | 20 ± 13.59 | 18.11 ± 12.32 | 0.470 |
| Type of seizures | 0.095 | ||
| Focal Seizure | 11 (25.58) | 24 (42.11) | |
| Generalized seizure | 32 (74.42) | 33 (57.89) | |
| Drug regimen | 0.044 | ||
| • Mono-therapy | 22 (51.16) | 15 (26.32) | |
| • Bi-therapy | 14 (32.56) | 27 (47.37) | |
| • Poly-therapy | 7 (16.28) | 15 (26.32) | |
| QOLIE-31-Domains∗ | |||
| Seizure worry | 60.53 ± 3.50 | 46.87 ± 9.04 | 0.0001 |
| Overall quality of life | 54.97 ± 5.51 | 39.40 ± 7.59 | 0.0001 |
| Emotional wellbeing | 54.74 ± 4.46 | 46.42 ± 7.22 | 0.0001 |
| Energy/fatigue | 59.16 ± 3.32 | 50.19 ± 7.31 | 0.0001 |
| Cognitive function | 60.21 ± 4.35 | 49.12 ± 10.21 | 0.0001 |
| Medication effects | 57.69 ± 3.53 | 46.96 ± 4.86 | 0.0001 |
| Social functioning | 53.25 ± 3.94 | 42.35 ± 10.01 | 0.0001 |
| overall weighted average health-related quality of life score | 57.02 ± 2.23 | 45.82 ± 6.28 | 0.0001 |
(∗Data are represented as mean ± SD, P value = 0.001).