Table 3.

Change of the selected spectral-domain optical coherence tomography parameters over the 6-month follow-up period.

Parameter	Mean thickness*	Mean change*	P value†
Central foveal retinal thickness (µm)
Baseline	225.9 ± 28.2
Day 30/Day 45	228.5 ± 31.3	2.4 ± 10.2	0.820
Day 180	232.3 ± 43.4	6.4 ± 19.2	0.080
Central foveal ONL thickness (µm)
Baseline	54.3 ± 13.9
Day 30/Day 45	53.3 ± 10.7	− 1.1 ± 8.5	0.815
Day 180	57.7 ± 15.7	3.4 ± 7.7	0.091
ONL thickness of the internal ETDRS ring (µm)
Baseline	37.7 ± 11.4
Day 30/Day 45	42.4 ± 8.6	4.7 ± 8.4	< 0.001
Day 180	42.7 ± 9.8	5.0 ± 5.7	0.009

ETDRS early treatment diabetic retinopathy study, OCT optical coherence tomography (OCT), ONL outer nuclear layer.

*Data reported as mean ± standard deviation.

^†p-values are obtained by generalized estimating equation regression models; statistically significant p-values are shown in bold.