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. 2022 Oct 21;13:6276. doi: 10.1038/s41467-022-34009-x

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — a Structural comparisons of the ABL–, PTH– and LA-PTH–bound (PDB 6NBF) PTH1R complexes. Structures were aligned by the TMD of PTH1R. b 3D-variability analysis of the ABL–, PTH– and LA-PTH–bound PTH1R–Gs complexes. Superimposition of models built into density maps corresponding to frame 000 and frame 019 of components 1 in Supplementary Movies. 1, 2 and 3.