Table 1.
Patient characteristics in all performed cycles.
| Overall | NR | POSEIDON | p | ||||
|---|---|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | ||||
| No. cycles | 374 | 124 | 53 | 77 | 36 | 84 | |
| Age (yrs)a | 35.47 (4.28) | 33.59 (3.93) | 32.32 (1.66) | 37.56 (2.31) | 31.97 (2.50) | 39.81 (3.20) | 0.000 |
| No. prev. preg.b | 0.00 [0.00, 8.00] | 0.00 [0.00, 5.00] | 0.00 [0.00, 5.00] | 1.00 [0.00, 5.00] | 0.00 [0.00, 5.00] | 1.00 [0.00, 8.00] | 0.000 |
| HT (m)a | 1.61 (0.05) | 1.61 (0.05) | 1.60 (0.05) | 1.61 (0.05) | 1.60 (0.06) | 1.62 (0.05) | 0.321 |
| BW (kg)a | 59.21 (10.62) | 60.14 (10.70) | 56.19 (8.24) | 58.26 (8.79) | 56.61 (15.74) | 61.71 (10.09) | 0.007 |
| BMI (kg/m2)a | 22.80 (3.89) | 23.19 (3.93) | 21.88 (3.40) | 22.32 (3.01) | 22.15 (6.45) | 23.51 (3.23) | 0.027 |
| Infert. Dur. (mo)b | 24.00 [1.00, 156.00] | 24.00 [2.00, 144.00] | 36.00 [8.00, 120.00] | 36.00 [1.00, 156.00] | 24.00 [5.00, 72.00] | 26.00 [2.00, 144.00] | 0.000 |
| Infert type (%)c | |||||||
| Prim | 233 (62.3) | 95 (76.6) | 40 (75.5) | 33 (42.9) | 31 (86.1) | 33 (39.3) | 0.000 |
| Sec | 141 (37.7) | 29 (23.4) | 13 (24.5) | 44 (57.1) | 5 (13.9) | 51 (60.7) | |
| Infert factor (%)c | |||||||
| Male | 67 (17.9) | 33 (26.6) | 15 (28.3) | 9 (11.7) | 2 (5.6) | 8 (9.5) | 0.000 |
| Female | 172 (46.0) | 59 (47.6) | 19 (35.8) | 33 (42.9) | 16 (44.4) | 45 (53.6) | |
| Both | 32 (8.6) | 10 (8.1) | 7 (13.2) | 10 (13.0) | 1 (2.8) | 4 (4.8) | |
| Unexpl | 103 (27.5) | 22 (17.7) | 12 (22.6) | 25 (32.5) | 17 (47.2) | 27 (32.1) | |
| FSHb (mIU/mL) | 6.17 [0.11, 49.19] | 5.01 [0.11, 14.20] | 7.12 [1.20, 14.20] | 6.35 [2.47, 34.64] | 6.90 [1.84, 49.19] | 7.74 [0.19, 30.60] | 0.000 |
| AMHb (ng/mL) | 2.08 [0.01, 23.94] | 4.51 [1.44, 23.94] | 2.87 [1.23, 12.31] | 1.78 [0.77, 7.26] | 0.31 [0.01, 4.15] | 0.40 [0.02, 1.17] | 0.000 |
| AFCb | 8.00 [0.00, 39.00] | 12.00 [2.00, 39.00] | 10.00 [0.00, 16.00] | 8.00 [2.00, 18.00] | 5.00 [2.00, 8.00] | 3.00 [0.00, 10.00] | 0.000 |
| Preov. fol.b | 10.00 [1.00, 76.00] | 21.00 [10.00, 76.00] | 10.00 [2.00, 18.00] | 9.00 [1.00, 18.00] | 5.00 [1.00, 21.00] | 4.00 [1.00, 42.00] | 0.000 |
Continuous variables are presented as either amean (SD) or bmedian [interquartile range]. Categorical variables are presented as cnumber of cycles (%). A p-value < 0.05 was considered statistically significant. NR normal responder, No. number, yrs years, prev. previous, HT height, BW body weight, BMI body mass index, Infert. Infertility, Dur. Duration, mo months, prim. Primary, sec. secondary, unexpl. Unexplained, FSH follicle stimulation hormone, AMH anti-Mullerian-hormone, AFC antral follicle count, Preov. fol. preovulatory follicles, POSEIDON patient-oriented strategies encompassing individualized oocyte number.