Table 4.

Correlations of calculated biomarkers to somatometric data and response to oral glucose tolerance testing (NHANES cohort) or M-value (clamp cohort), respectively.

	HOMA-Beta	HOMA-IR	QUICKI	SPINA-GBeta	SPINA-GR
NHANES cohort
BMI	0.416†††	0.516†††	− 0.516†††	0.500†††∆	− 0.513†††
Waist circumference	0.339†††	0.498†††	− 0.498†††	0.456†††∆	− 0.502†††∆◊
Triceps skinfold	0.371†††	0.331†††	− 0.331†††	0.363†††	− 0.320†††∆◊
Subscapular skinfold	0.320†††	0.383†††	− 0.383†††	0.375†††∆	− 0.381†††
2 h glucose in oGTT	0.050*	0.347†††	− 0.347†††	0.235†††∆	− 0.368†††∆◊
Glucose rise in oGTT	0.091†	0.245†††	− 0.245†††	0.187†††∆	− 0.256†††∆◊
HbA1c	− 0.063***	0.219†††	− 0.219†††	0.104††∆	− 0.243†††∆◊
Clamp cohort
BMI	0.193	0.056	− 0.054	0.089∆	− 0.049
Waist circumference	0.374***	0.274**	− 0.275**	0.295**	− 0.273**
WHR	0.276**	0.245*	− 0.242*	0.248*	− 0.250*
Truncal fat	0.379***	0.412***	− 0.412†	0.408†	− 0.411†
Fat (DXA)	0.409†	0.427†	− 0.428†	0.429†	− 0.429†
FFM	0.238*	0.078	− 0.077	0.113∆	− 0.071
M value	− 0.361***	− 0.311**	0.314**	− 0.334***	0.305**

Shown are rho values of Spearman’s rank correlation. p * < 0.05, ** < 0.01, *** < 0.001, ^† < 1e–4, ^†† < 1e–6, ^††† < 1e–15 for correlations. ∆ Different from correlation for corresponding HOMA parameter; ◊ different from correlation for QUICKI, based on Zou’s confidence intervals.