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. 2022 Mar 26;37(12):3009–3018. doi: 10.1007/s00467-022-05532-2

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Fig. 1 — Different outcomes of renal tubular cells after injuries: A after a mild injury, the cells can be completely repaired through reprogramming (adaptive repair); B after a repeated or severe injury: a, cell necrosis or apoptosis; b, EMT contributes to fibrosis and collagen deposition after reprogramming; c, SASP secretion evolves into chronic cellular senescence