Table 1.
Baseline characteristics of two groups
| rTSMS group (n = 50) | Sham group (n = 50) | P value | |
|---|---|---|---|
| Age, years (SD) | 68.66 (8.69) | 70.98 (7.30) | 0.15 |
| Sex, male/female | 24/26 | 23/27 | |
| Disease duration (SD) | 7.68 (5.44) | 5.74 (5.05) | 0.06 |
| Modified Hoehn and Yahr Scale | |||
| Score 2 | 1 | 0 | |
| Score 2.5 | 0 | 1 | |
| Score 3 | 19 | 16 | |
| Score 3.5 | 19 | 24 | |
| Score 4 | 10 | 9 | |
| Score 4.5 | 1 | 0 | |
| Use of drugs | |||
| Levodopa | 45 | 46 | |
| Dopamine agonist | 27 | 25 | |
| COMT inhibitor | 9 | 4 | |
| MAO-β blockers | 13 | 13 | |
| Amantadine | 1 | 1 | |
| LEDD (SD) | 557.7 (166.8) | 532.0 (193.1) | 0.63 |
| UPDRS total (SD) | 74.94 (24.33) | 75.22 (23.23) | 0.95 |
| UPDRS I (0–16) (SD) | 5.72 (3.35) | 6.30 (2.68) | 0.34 |
| UPDRS II (0–52) (SD) | 21.18 (7.81) | 22.12 (6.81) | 0.52 |
| UPDRS III (0–108) (SD) | 46.24 (14.57) | 45.24 (15.03) | 0.73 |
| UPDRS IV (0–23) (SD) | 1.80 (2.32) | 1.56 (2.20) | 0.54 |
| TUG (SD) | 10.43 (4.29) | 11.36 (5.51) | 0.34 |
| STEF, right (SD) | 84.06 (19.02) | 83.88 (13.018) | 0.050 |
| STEF, left (SD) | 83.36 (20.82) | 85.28 (15.07) | 0.60 |
| Flexion angle of spine (SD) | 19.5 (12.1) | 23.2 (14.2) | 0.17 |
| FAB (SD) | 14.80 (2.25) | 13.63 (3.20) | 0.054 |
rTSMS repetitive trans-spinal magnetic stimulation, COMT catechol-O-methyltransferase, MAO monoamine oxidases, LEDD levodopa equivalent daily dose, UPDRS Unified Parkinson’s Disease Rating Scale, TUG Timed Up and Go test, STEF simple test for evaluating hand function, FAB Frontal Assessment Battery