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. 2022 Oct 7;19(4):1133–1144. doi: 10.1007/s13311-022-01297-6

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — Age-related changes in motor unit size. A–D: Motor units from the omohyoid (A, B) and extraocular (C, D) muscles of young adult (A, C) and old (B, D) mice. E, F: Motor unit size in young adult and old omohyoid (E) and extraocular (F) muscles showing the increase in size specifically in the omohyoid motor units due to sprouting of surviving motor neurons. (Reproduced from Valdez et al. [83])