Figure 3.

Deletion of Shh in catecholaminergic neurons mediated by Th-driven IRES-cre does not affect DA neuron survival in 7–8-month-old mice

Representative images from WT or THcre-shh cKO mice at 7–8 months of age in the STR (A and B) and SN (D and E) immunostained for TH. Quantification of striatal TH fiber density (C) or Unbiased stereological counts of DA neurons in the SN (F). Each data point represents an individual mouse. Mean + SEM. No significant difference between groups (Student’s t test). Scale bar = 50μm.