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. 2022 Oct 7;25(11):105278. doi: 10.1016/j.isci.2022.105278

Figure 6.

Figure 6

DA neurons are not a critical source of SHH ligand for SVZ NSCs

We observe no difference in the number of proliferating cells (A and B) or neuroblasts (C and D) in 3-month-old WT or DATcre-shh cKO mice at the SVZ, suggesting that DA neurons are not an active source of SHH ligand for SVZ NSCs. Mean + SEM.

(E and F) Quantification from multiple sections averaged in each animal. Each data point represents the average from an individual mouse. Mean + SEM. No significant difference between groups (Student’s t test). Scale bar = 100um.