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. 2022 Oct 14;8(10):e11071. doi: 10.1016/j.heliyon.2022.e11071

Table 2.

The distribution of CK-MM concentration in relation to gender, gestational age (GA), birth weight (BW) and age at sampling subgroups.

Group N CK-MM Percentile values (ng/mL)
Median 25th 75th 99th 99.7th
Gender Male 44268 113 73.0 173 544 805.8
Female 18285 98.7 65.9 151 469 658.3
Gestational age Premature
<32 W 327 28.9 16.9 50.8 196.4 263.3
32–36 W 2197 48.5 28.4 80.4 316 687.4
36–37 W 2183 77.4 50 119 394.3 649.8
Term 37–42 W 57812 112 74.6 171 529 772
Overdue ≥42 W 34 144 104.5 208.5 675.6 694.1
Birth weight Low BW
<1000 g 41 34.6 21.8 81.4 161.2 166
1000–1500 g 227 30.6 16.8 56 196.4 232.7
1500–2500 g 3924 66.5 38 111 448.8 892.3
Normal BW 2500–4000 g 56612 112 73.9 170 526 751.3
Macrosomia ≥4000 g 1749 98.2 66 151.5 556 804.3
Age at sampling 24–48 h 13869 159 107 234 669.3 993.4
48–72 h 29103 108 73.4 161 476 676.4
72–168 h 18521 85.4 57.3 126 388 581.3
≥168 h 1060 33.1 22 49.9 210.2 376.4

The distribution of CK-MM was significantly different between males and females (Mann-Whitney U test, P < 0.001).

Differences in the CK-MM concentrations for each subgroup of gestational age were statistically significant (Kruskal-Wallis test, P < 0.001).

Differences in the CK-MM concentrations for each subgroup of birth weight were statistically significant (Kruskal-Wallis test, P < 0.001).

The differences in the CK-MM concentrations for each subgroup of age at sampling were statistically significant (Kruskal-Wallis test, P < 0.001).