Table 1.

Results from lipidomic analysis of nuclear fraction from hepatocytes from control and L-CKO mice (n = 3 per group)

Abbreviation	Full name	Mol % of total lipid			Mean ± SEM	Mol % of total lipid			Mean ± SEM	P
		Contol 1	Control 2	Control 3		L-CKO 1	L-CKO 2	L-CKO 3
SM	Sphingomyelin	1.9440	1.2471	1.5860	1.5924 ± 0.201	1.7926	1.8697	3.0520	2.2381 ± 0.4075	0.2284
PA	Phosphatidic acid	0.2915	0.3262	0.2270	0.2815 ± 0.029	0.2615	0.3386	0.3846	0.3282 ± 0.0359	0.3697
PC	Phosphatidylcholine	3.8017	2.2881	2.5536	2.8811 ± 0.4666	3.5386	4.5045	5.6653	4.5694 ± 0.6148	0.094
PE	Phosphatidylethanolamine	19.3668	12.1711	13.1774	14.9050 ± 2.2505	11.1433	14.6894	16.9155	14.2493 ± 1.681	0.8268
PS	Phosphatidylserine	1.2359	0.7908	0.4832	0.8366 ± 0.2185	1.0402	0.9940	2.1940	1.4093 ± 0.3925	0.2713
PI	Phosphatidylinositol	1.8524	1.0944	1.3883	1.4450 ± 0.0202	1.3933	1.2974	2.3959	1.6951 ± 0.0022	0.5785
TG	Triacylglycerol	2.6072	2.4990	3.9703	3.0255 ± 0.4734	26.6863	19.7849	24.9933	23.8215 ± 2.077	0.0006a
PC/PE		0.1963	0.1880	0.1938	0.1932 ± 0.0024	0.3176	0.3066	0.3349	0.3197 ± 0.0082	0.0001a
PA/PC		0.0767	0.1426	0.0889	0.1027 ± 0.0036	10.7123	14.7780	7.7100	11.0667 ± 0.0021	0.4014

The abbreviated and full names of lipid species are shown in the left two columns. The levels of each lipid species are represented as mol % of total lipid composition. The results from three different control and L-CKO mice are provided as well as means ± SEM (n = 3 per group).

^aP < 0.001, by unpaired Student’s t test.