Table 1.
Baseline Characteristics and Demographics of Patients
| Parameters | Total | Category 1 (Fundus Tessellation) | Category 2 (Diffuse Atrophy) | Category 3 (Patchy Atrophy) | P * |
|---|---|---|---|---|---|
| Eyes, n (%) | 78 (100.0) | 14 (17.9) | 33 (42.3) | 31 (39.7) | |
| Age (y), mean ± SD (range) | 64.1 ± 10.0 (45∼86) | 64.8 ± 10.7 (47∼79) | 61.3 ± 9.1 (45∼83) | 66.6 ± 10.1 (52∼86) | 0.101 |
| Gender (female/male), n (%) | 67 (85.9)/11 (14.1) | 14(100.0)/0 | 27 (81.8)/6 (18.2) | 26 (83.9)/5 (16.1) | 0.324 |
| Mean axial length (mm), mean ± SD (range) | 30.0 ± 1.4 (26.2∼33.4) | 28.5 ± 1.1 (26.2∼29.8) | 29.8 ± 1.4 (27.1∼32.2) | 30.7 ± 1.1 (28.8∼33.4) | <0.001 |
| Presence of lacquer cracks, n (%) | 24 (30.8) | 1 (7.1) | 13 (39.4) | 10 (32.3) | 0.095 |
| History of myopic CNV, n (%) | 15 (19.2) | 0 (0.0) | 7 (21.2) | 8 (25.8) | 0.123 |
| Presence of posterior staphyloma, n (%) | 48 (61.5) | 7 (50.0) | 21 (63.6) | 20 (64.5) | 0.649 |
| BCVA (logMAR), mean ± SD (range; Snellen equivalent) | 0.38 ± 0.30 (−0.18∼1.70; 20/48) | 0.34 ± 0.26 (0.15∼2.50; 20/44) | 0.37 ± 0.28 (−0.18∼1.22; 20/47) | 0.41 ± 0.33 (0.50∼1.70; 20/51) | 0.399 |
| Macular sensitivity (dB), mean ± SD (range)† | 18.8 ± 4.8 (2.7∼26.8) | 22.0 ± 2.7 (16.9∼26.8) | 19.9 ± 3.5 (7.9∼25.6) | 16.2 ± 5.4 (2.7∼22.6) | <0.001 |
| Choroidal thickness (µm), mean ± SD (range)† | 29.6 ± 17.4 (5.4∼84.9) | 48.8 ± 12.0 (28.7∼65.2) | 32.3 ± 17.0 (11.0∼84.9) | 18.1 ± 9.6 (5.4∼44.3) | <0.001 |
| Outer retinal thickness (µm), mean ± SD (range)† | 92.0 ± 21.5 (37.1∼200.6) | 98.7 ± 4.0 (90.4∼105.2) | 98.5 ± 25.7 (73.8∼200.6) | 82.0 ± 17.4 (37.1∼120.7) | 0.003 |
| Testing points, n (%) | <0.001 | ||||
| Zone 1 | 158 (5.8) | 0 (0.0) | 0 (0.0) | 158 (15.1) | |
| Zone 2 | 219 (8.1) | 0 (0.0) | 0 (0.0) | 219 (21.0) | |
| Zone 3 | 2333 (86.1) | 501 (100.0) | 1164 (100.0) | 668 (63.9) |
*
One-way ANOVA.
†
Mean and range of average of 36 testing points per eye.