Table 1.
Baseline characteristics
| SC group (n = 8) | IV group (n = 8) | Placebo (n = 7) | P-value | |
|---|---|---|---|---|
| Age (years)a | 32.6 (0.95) | 30.1 (4.30) | 33 (6.53) | 0.39 |
| Height (m)a | 1.64 (0.05) | 1.62 (0.05) | 1.63 (0.03) | 0.65 |
| Weight (kg)a | 111.1 (34.9) | 94.4 (12.4) | 86.4 (19.0) | 0.16 |
| BMI (kg/m2)a | 41.1 (12.0) | 36.0 (6.06) | 32.8 (7.84) | 0.22 |
| Gestational age (weeks)a | 38.7 (1.11) | 38.0 (1.11) | 37.5 (0.76) | 0.12 |
| American Society of Anesthesiologists (ASA) Physical Status (Classification I-Vc, n (%))b | 0.68 | |||
| ASA II | 5 (62.5) | 7 (87.5) | 6 (85.7) | |
| ASA III | 3 (37.5) | 1 (12.5) | 1 (14.3) | |
| Ethnicityb | 0.86 | |||
| Caucasian | 5 (62.5) | 6 (75) | 5 (71.4) | |
| African American | 3 (37.5) | 2 (25) | 1 (14.3) | |
| Hispanic | 0 (0) | 0 (0) | 1 (14.3) | |
| Insurance statusb | 0.75 | |||
| Insured | 5 (62.5) | 6 (75) | 4 (57.1) | |
| Uninsured | 3 (37.5) | 2 (25) | 3 (37.5) | |
| Pre-operative screeninga | ||||
| Anxiety (GAD-7) | 6.13 (8.20) | 6.25 (5.55) | 7.29 (2.93) | 0.92 |
| Depression (EPDS) | 6.25 (6.27) | 5 (4.78) | 8.29 (4.72) | 0.50 |
| Psychosocial stress (ANRQ) | 17 (14.4) | 14.9 (9.25) | 26.3 (13.0) | 0.20 |
| Psychiatric historyb | ||||
| Any psychiatric history | 2 (25) | 1 (12.5) | 7 (100) | 0.05 |
| PPD | 2 (25.0) | 0 (0) | 2 (28.6) | 0.78 |
| MDD | 1 (12.5) | 0 (0) | 3 (42.9) | 0.36 |
| Anxiety | 2 (25.0) | 2 (25.0) | 6 (85.7) | 0.03 |
| Mood Disorder | 0 (0) | 0 (0) | 2 (28.6) | - |
| Personality Disorder | 0 (0) | 0 (0) | 0 (0) | - |
| Psychotic Disorder | 0 (0) | 0 (0) | 0 (0) | - |
| Premenstrual Syndrome | 0 (0) | 0 (0) | 0 (0) | - |
| Premenstrual Dysmorphic Disorder | 0 (0) | 0 (0) | 0 (0) | - |
| Panic Disorder | 0 (0) | 1 (12.5) | 0 (0) | - |
| Bipolar Affective Disorder | 0 (0) | 0 (0) | 1 (14.3) | - |
| Obsessive Compulsive Disorder | 0 (0) | 0 (0) | 1 (14.3) | - |
Data are presented as: an (SD), bn (%)
GAD-7 General Anxiety Disorder scale, EPDS Edinburgh Postpartum Depression Scale, ANRQ Antenatal Risk Questionnaire
cAmerican Society of Anesthesiologists (ASA) Physical Status Classification System is designed to assess and communicate a patient’s pre-anesthesia medical co-morbidities. A pregnant woman cannot be classified as ASA I, is classified as ASA II if they have no medical co-morbidities and is classified as ASA III if they have mild medical co-morbidities