TABLE 7.
Agreement between 24-h and 6-h CD4 counts by methoda
CD4 stratum and laboratory | n | Median CD4 count
|
Agreement, TruCount
|
Pb | Median CD4 count
|
Agreement, predicate
|
P | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
24-h | 6-h | 10th | 50th | 90th | 24-h | 6-h | 10th | 50th | 90th | ||||
All strata | |||||||||||||
All labs | 1,120 | 211 | 219 | −39 | −2 | 39 | <0.01 | 209 | 200 | −38 | 4 | 81 | <0.01 |
A | 224 | 269 | 279 | −26 | 6 | 56 | <0.01 | 289 | 254 | −12 | 25 | 115 | <0.01 |
B | 224 | 173 | 183 | −47 | −8 | 42 | <0.01 | 200 | 210 | −22 | 20 | 114 | <0.01 |
C | 224 | 237 | 224 | −18 | 1 | 56 | 190 | 194 | −45 | 0 | 65 | ||
D | 224 | 213 | 217 | −42 | −3 | 26 | <0.01 | 179 | 191 | −80 | −12 | 13 | <0.01 |
E | 224 | 186 | 192 | −56 | −9 | 10 | <0.01 | 158 | 177 | −34 | 0 | 47 | |
<200 | |||||||||||||
All labs | 560 | 104 | 108 | −23 | −3 | 15 | <0.01 | 109 | 103 | −26 | 0 | 33 | |
A | 80 | 171 | 173 | −16 | 4 | 26 | <0.05 | 152 | 144 | −12 | 10 | 160 | <0.01 |
B | 112 | 115 | 119 | −29 | −7 | 18 | <0.01 | 136 | 113 | −19 | 13 | 74 | <0.01 |
C | 112 | 60 | 58 | −13 | 0 | 14 | 39 | 49 | −34 | −1 | 28 | ||
D | 128 | 109 | 115 | −22 | −2 | 10 | <0.01 | 90 | 104 | −30 | −5 | 7 | <0.01 |
E | 128 | 104 | 115 | −26 | −6 | 2 | <0.01 | 87 | 96 | −34 | −2 | 19 | |
≥200 | |||||||||||||
All labs | 560 | 400 | 387 | −59 | −1 | 62 | 401 | 370 | −57 | 18 | 103 | <0.01 | |
A | 144 | 320 | 312 | −35 | 8 | 66 | 361 | 305 | −15 | 37 | 104 | <0.01 | |
B | 112 | 401 | 401 | −72 | −11 | 67 | 498 | 443 | −25 | 52 | 142 | <0.01 | |
C | 112 | 418 | 389 | −31 | 18 | 91 | <0.01 | 402 | 368 | −66 | 12 | 98 | |
D | 96 | 473 | 492 | −66 | −8 | 39 | 406 | 451 | −116 | −33 | 31 | <0.01 | |
E | 96 | 269 | 279 | −82 | −23 | 26 | <0.01 | 262 | 252 | −34 | 9 | 91 | <0.02 |
Agreement was determined by subtracting the 6-h absolute count from the 24-h absolute count (cells per microliter) obtained for the same sample by the same method. The estimated 10th, 50th, and 90th percentiles of the differences in absolute counts were determined.
P value for the estimated 50th percentile, the Wilcoxon signed-rank test.