Table 3.

Age-adjusted odds ratio (OR) and 95% confidence intervals (CI) for worse CDRS score and CDRS global rating versus better for those with worse visual function compared to those with better visual function (worse score or rating, worse performance) (N=144).

	Worse CDRS composite score vs. better		Worse CDRS global rating vs. better
	(N events = 38)		(N events = 57)
	OR (95% CI)	p-value	OR (95% CI)	p-value
Contrast sensitivity, log sensitivity
≥ 1.5 (better)	REF†		REF
< 1.5 (worse)	1.56 (0.59-4.09)	0.37	1.85 (0.74-4.65)	0.19
UFOV subtest 2‡, ms
< 150 (better)	REF		REF
150-350	3.24 (1.12-9.32)	0.03	3.15 (1.18-8.40)	0.02
> 350 (worse)	16.47 (3.65-74.38)	0.0003	17.09 (3.55-82.31)	0.0004
Trails B, minute
< 2.47 (better)	REF		REF
≥ 2.47 (worse)	1.44 (0.61-3.42)	0.40	2.11 (0.94-4.71)	0.07
MVPT3, score
≥ 8 (better)	REF		REF
< 8 (worse)	2.23 (0.52-9.51)	0.28	2.40 (0.58-9.90)	0.23
Overall visual field sensitivity, dB
> 22.4 (better)	REF		REF
≤ 22.4 (worse)	2.22 (0.89-5.52)	0.09	2.32 (0.97-5.58)	0.06
Peripheral visual field sensitivity, dB
> 19.5 (better)	REF		REF
≤ 19.5 (worse)	1.78 (0.73-4.34)	0.21	2.17 (0.93-5.08)	0.07
Upper visual field sensitivity, dB
> 22.2 (better)	REF		REF
≤ 22.2 (worse)	1.42 (0.59-3.42)	0.43	1.40 (0.61-3.22)	0.43
Lower visual field sensitivity, dB
> 22.1 (better)	REF		REF
≤ 22.1 (worse)	2.19 (0.90-5.34)	0.08	2.18 (0.93-5.10)	0.07
Left visual field sensitivity, dB
> 21.7 (better)	REF		REF
≤ 21.7 (worse)	1.73 (0.71-4.21)	0.23	1.74 (0.75-4.04)	0.19
Right visual field sensitivity, dB
> 21.9 (better)	REF		REF
≤ 21.9 (worse)	2.24 (0.93-5.39)	0.07	2.18 (0.94-5.05)	0.07
Gabor drifting grating threshold, Hz
≤ 0.14 (better)	REF		REF
> 0.14 (worse)	2.67 (1.14-6.26)	0.02	1.71 (0.79-3.71)	0.17

^†Reference

^‡116 participants completed this testing.