Figure 3.

GITR agonistic stimulation decreases esophageal squamous cell cancer progression. Mice treated with 4-NQO to induce ESCC received IgG antibody (A, C) or anti-GITR agonist antibody (B, D) for 2.5 weeks and were processed for hematoxylin/eosin staining. (E) Histological scoring of H&E staining for 4-NQO treated mice that received IgG or anti-GITR agonist antibody. n = 14. Scale bars for A, B = 500 µm. Scale bars for C, D = 50 µm. P = 0.0388 calculated by two-tailed Student’s t-test. Graph shows median with interquartile range.