Table 3.
Associations Between Acne Grades and Serum Sex Hormone Levels in Female Acne Patients
| Indicators | Grade I | Grade II | Grade III | Grade IV | KW-χ2 | p-value |
|---|---|---|---|---|---|---|
| FSH(IU/L) | 4.71(2.75–6.73) | 5.37(3.56–7.72) | 7.01(5.55–8.38) | 6.83(5.54–9.47) | 42.233 | <0.001 |
| LH(IU/L) | 6.62(3.46–12.73) | 6.84(4.64–10.95) | 6.55(4.61–10.41) | 7.13(4.52–10.16) | 0.773 | 0.856 |
| E2(pmol/L) | 595.86(285.72–1054.28) | 317.53(206.77–479.50) | 152.89(99.42–202.34) | 125.59(91.21–158.81) | 225.324 | <0.001 |
| P(nmol/L) | 11.07(0.75–41.40) | 2.09(0.48–23.73) | 0.71(0.38–1.29) | 0.65(0.43–1.04) | 63.766 | <0.001 |
| T(nmol/L) | 0.56(0.10–0.94) | 0.89(0.59–1.26) | 1.11(0.73–1.48) | 1.40(0.81–1.90) | 64.988 | <0.001 |
| PRL(mIU/L) | 283.94(156.20–427.85) | 256.93(142.10–415.72) | 239.00(116.50–357.39) | 258.86(144.94–389.80) | 6.650 | 0.232 |
| A/E | 0.84(0.56–1.15) | 2.88(1.95–3.76) | 7.02(5.47–9.23) | 11.98(8.09–14.24) | 416.437 | <0.001 |
Abbreviations: KW, Kruskal–Wallis test; FSH, follicle-stimulating hormone; LH, luteinizing hormone; E2, estradiol; P, progesterone; T, testosterone; PRL, prolactin; A/E, ratio of androgen to estrogen.