Table 3.
Comparison of Adverse Events between 5 and 10 mg Olanzapine Groups
| Adverse events | Olanzapine group | |||||||
|---|---|---|---|---|---|---|---|---|
| 5 mg (n = 70), n (%) | 10 mg (n =70), n (%) | |||||||
| Grade | Grade | |||||||
| Any | 1 | 2 | ≥3 | Any | 1 | 2 | ≥3 | |
| Somnolence | 49 (70) | 40 (57) | 9 (13) | 0 | 39 (56) | 27 (39) | 12 (17) | 0 |
| Dysguesia | 44 (63) | 41 (59) | 3 (4) | 0 | 34 (49) | 28 (40) | 6 (9) | 0 |
| Dry mouth | 43 (61) | 43 (61) | 0 | 0 | 40 (57) | 37 (53) | 3 (4) | 0 |
| Hiccups | 40 (57) | 38 (54) | 2 (3) | 0 | 31 (44) | 30 (43) | 1 (1) | 0 |
| Anorexia | 40 (57) | 35 (50) | 5 (7) | 0 | 29 (41) | 21 (30) | 8 (11) | 0 |
| Nausea | 36 (51) | 30 (43) | 6 (9) | 0 | 32 (46) | 25 (36) | 7 (10) | 0 |
| Constipation | 35 (50) | 33 (47) | 2 (3) | 0 | 38 (54) | 36 (51) | 2 (3) | 0 |
| Insomnia | 35 (50) | 30 (43) | 4 (6) | 1 (1) | 30 (43) | 23 (33) | 6 (9) | 1 (1) |
| Vomiting | 18 (26) | 13 (19) | 5 (7) | 0 | 11 (16) | 9 (13) | 2 (3) | 0 |
| Diarrhea | 6 (9) | 5 (7) | 1 (1) | 0 | 8 (11) | 7 (10) | 1 (1) | 0 |
| AKI | 4 (6) | - | - | 4 (6) | 4 (6) | - | - | 4 (6) |
| Muscle rigidity | 3 (4) | 3 (4) | 0 | 0 | 5 (7) | 4 (6) | 0 | 1 (1) |
| FN | 2 (3) | - | - | 2 (3) | 3 (4) | - | - | 3 (4) |
| Thrombocytopenia | 0 | 0 | 0 | 0 | 1 (1) | 0 | 0 | 1 (1) |
| Hyponatremia | 1 (1) | 0 | 0 | 1 (1) | 0 | 0 | 0 | 0 |
Abbreviations: AKI, acute kidney injury; FN, febrile neutropenia