Table 3.
Differences in the Mean Protein Expression of Bax, Bcl-2 and Bax/Bcl-2 Ratio before and after Chemotherapy and Death among Pediatric ALL
| Protein type | Outcome (N=17) | Pb | |||
|---|---|---|---|---|---|
| Alive (N=11) Mean (SD) | Pa | Died (N=6) Mean (SD) | |||
| Before | After | ||||
| Mean (SD) | Mean (SD) | ||||
| Bax expression | 22.8 (25.86) | 37.1 (16.55) | 0.062 | 14.2 (6.55) | 0.763 |
| Bcl2 expression | 22.6 (21.83) | 9.9 (9.99) | 0.075 | 22.9 (27.26) | 0.366 |
| Bax/Bcl-2 expression | 1.74 (1.846) | 6.17 (4.139) | 0.021 | 3.88 (4.663) | 0.763 |
*, Wilcoxon-Signed Rank test between before and after induction phase chemotherapy; b,Mann-Whitney U test between the living (before) and the dead