Table 5.
Differences in Bax, Bcl-2, and Bax/Bcl-2 Ratio Protein Expression before Chemotherapy Based on the Classification of Pediatric ALL Diagnosis
Diagnoses classification | Outcome (n=17) | ||
---|---|---|---|
Bax Mean (SD) | Bcl-2 Mean (SD) | Bax/Bcl Ratio Mean (SD) | |
ALL type | |||
ALL-L1 (N=16) | 20.7 (21.49) | 23.2 (23.65) | 2.63 (3.219) |
ALL-L2 (N=1) | 4.2 | 0.703 | 0.31 |
Immunophenotyping result | |||
B-cell ALL (N=13) | 19.6 (24.35) | 25.9 (25.54) | 2.72 (3.616) |
T-cell ALL (N=4) | 20.0 (4.88) | 12.2 (4.94) | 1.75 (0.501) |
Risk classification | |||
Standard risk ALL (N=7) | 13.4 (72.9) | 14.5 (10.53) | 1.49 (1.210) |
High risk ALL (N=10) | 24.2 (26.64) | 28.3 (27.95) | 3.19 (3.942) |
The statistical test used is the Mann Whitney U test