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. 2022 May;23(5):1679–1685. doi: 10.31557/APJCP.2022.23.5.1679

Table 5.

Differences in Bax, Bcl-2, and Bax/Bcl-2 Ratio Protein Expression before Chemotherapy Based on the Classification of Pediatric ALL Diagnosis

Diagnoses classification Outcome (n=17)
Bax Mean (SD) Bcl-2 Mean (SD) Bax/Bcl Ratio Mean (SD)
ALL type
ALL-L1 (N=16) 20.7 (21.49) 23.2 (23.65) 2.63 (3.219)
ALL-L2 (N=1) 4.2 0.703 0.31
Immunophenotyping result
B-cell ALL (N=13) 19.6 (24.35) 25.9 (25.54) 2.72 (3.616)
T-cell ALL (N=4) 20.0 (4.88) 12.2 (4.94) 1.75 (0.501)
Risk classification
Standard risk ALL (N=7) 13.4 (72.9) 14.5 (10.53) 1.49 (1.210)
High risk ALL (N=10) 24.2 (26.64) 28.3 (27.95) 3.19 (3.942)

The statistical test used is the Mann Whitney U test