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. 2022 Oct 22;20:484. doi: 10.1186/s12967-022-03684-1

Table 1.

The baseline characteristics of participants

TG/HDL-C Quintile Q1(< 0.4) Q2(≥ 0.4– < 0.6) Q3(≥ 0.6– < 0.8) Q4(≥ 0.8– < 1.1) Q5(≥ 1.1) P-value
N 30631 30631 30626 30631 30644
Age(years) 36.6 ± 12.0 38.0 ± 13.0 39.3 ± 13.8 40.8 ± 14.3 43.2 ± 14.3  < 0.001
Gender  < 0.001
Female 24953 (81.5%) 21099 (68.9%) 17684 (57.7%) 13362 (43.6%) 8763 (28.6%)
Male 5678 (18.5%) 9532 (31.1%) 12942 (42.3%) 17269 (56.4%) 21881 (71.4%)
BMI(kg/m2) 20.2 ± 1.9 20.6 ± 2.0 21.0 ± 2.1 21.4 ± 2.0 22.2 ± 1.8  < 0.001
GGT(U/L) 16.4 (13.0–24.0) 18.0 (14.0–25.0) 19.0 (15.0–27.0) 21.0 (16.0–30.8) 25.0 (19.0–38.0)  < 0.001
ALT(U/L) 14.0 (10.0–20.0) 14.0 (11.0–20.6) 15.0 (11.0–22.0) 16.0 (12.0–23.6) 19.0 (14.0–26.0)  < 0.001
AST(U/L) 20.0 (17.0–24.0) 20.0 (17.0–24.0) 20.0 (17.0–24.4) 21.0 (18.0–25.0) 22.0 (18.8–26.0)  < 0.001
ALB(g/L) 44.4 ± 3.0 44.4 ± 3.0 44.5 ± 3.1 44.6 ± 3.0 44.8 ± 3.0  < 0.001
GLB(g/L) 29.1 ± 3.7 29.3 ± 3.8 29.4 ± 3.8 29.4 ± 3.8 29.4 ± 3.8 0.001
TB(umol/L) 12.1 ± 5.1 12.0 ± 5.0 12.1 ± 5.0 12.1 ± 5.1 12.1 ± 5.1  < 0.001
DBIL(umol/L) 1.9 (1.4–2.6) 1.9 (1.4–2.6) 1.9 (1.3–2.6) 1.8 (1.3–2.5) 1.8 (1.2–2.5)  < 0.001
BUN(mmol/L) 4.3 ± 1.2 4.3 ± 1.2 4.3 ± 1.3 4.4 ± 1.3 4.5 ± 1.3  < 0.001
Scr(umol/L) 70.6 ± 14.7 74.1 ± 18.1 77.0 ± 22.9 80.6 ± 22.6 84.6 ± 26.3  < 0.001
UA(umol/L) 231.9 ± 68.0 249.0 ± 74.6 266.3 ± 78.4 288.7 ± 81.8 321.2 ± 85.5  < 0.001
FPG(mmol/L) 4.9 ± 0.4 5.0 ± 0.4 5.0 ± 0.4 5.1 ± 0.5 5.1 ± 0.5  < 0.001
TC(mmol/L) 4.5 ± 0.7 4.4 ± 0.7 4.4 ± 0.7 4.5 ± 0.7 4.6 ± 0.7  < 0.001
TG(mmol/L) 0.6 (0.5–0.7) 0.8 (0.7–0.9) 1.0 (0.9–1.1) 1.2 (1.1–1.4) 1.8 (1.5–2.2)  < 0.001
HDL-C(mmol/L) 1.8 ± 0.3 1.6 ± 0.3 1.5 ± 0.3 1.3 ± 0.2 1.2 ± 0.2  < 0.001
LDL-C(mmol/L) 2.0 ± 0.5 2.1 ± 0.5 2.2 ± 0.5 2.3 ± 0.5 2.4 ± 0.4  < 0.001
TG/HDL-C 0.4 (0.3–0.4) 0.5 (0.5–0.5) 0.7 (0.6–0.7) 0.9 (0.8–1.0) 1.5 (1.3–1.9)  < 0.001

Values are n (%) or mean ± SD or median (quartile)

ALB albumin, ALT alanine aminotransferase, AST aspartate aminotransferase, BMI body mass index, BUN blood urea nitrogen, Scr serum creatinine, DBIL direct bilirubin, TB total bilirubin, FPG fasting plasma glucose, GGT γ-glutamyl transpeptidase, GLB globulin, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, TC total cholesterol, TG triglyceride, UA uric acid, TG/HDL-C triglyceride-to-high-density lipoprotein cholesterol ratio