Table 1. Comparison of the clinical and laboratory characteristics between patient groups.
The table shows that the age and proportion of smoking in the CA-AKI group were significantly higher than the no-CA-AKI group. Concerning laboratory data, baseline serum creatinine, RDW, NLR and PLR in the CA-AKI group were higher than those in the no-CA-AKI group, while eGFR, hemoglobin, red blood cell count, white blood cell count, and albumin at baseline were significantly lower than those in the no-CA-AKI group.
| Variables | No-CA-AKI group (n = 607) | CA-AKI group (n = 25) | P value |
|---|---|---|---|
| Clinical characteristics | |||
| Age [years] | 61.00 (51.00, 71.00) | 72 (61.00, 81.00) | 0.0002 |
| Male [n (%)] | 375 (61.78) | 17 (68.00) | 0.675 |
| Diabetes [n (%)] | 123 (20.26) | 4 (16.00) | 0.800 |
| Hypertension [n (%)] | 268 (44.15) | 11 (44.00) | 1.000 |
| Coronary heart disease [n (%)] | 78 (12.85) | 5 (20.00) | 0.214 |
| Smoking [n(%)] | 138 (22.73) | 11 (44.00) | 0.027 |
| Statins [n(%)] | 225 (37.07) | 7 (28.00) | 0.405 |
| ACEI/ARB [n(%)] | 82 (13.51) | 4 (16.00) | 0.953 |
| Total amount of contrast (ml, x ± s) | 90.91 ± 16.12 | 85.93 ± 19.91 | 0.106 |
| Laboratory characteristics | |||
| Baseline serum creatinine (µmol/L, M(1/4, 3/4)) | 80.0 (65.00, 99.00) | 95.0 (85.00, 130.50) | 0.0002 |
| Baseline eGFR (ml⋅ minsymbol−1⋅ (1.73 m2)symbol−1) | 84.38 (64.77,98.71) | 61.12 (47.73,74.44) | <0.0001 |
| Hemoglobin (g/L) | 131.0 (119.0, 141.0 ) | 112.0 (93.0,138.5 ) | 0.0039 |
| Red cell distribution width (%) | 13.20 (12.70, 13.80) | 15.10 (13.30, 16.35) | <0.0001 |
| Red blood cell count(×1012/L) | 4.42 ± 0.65 | 4.12 ± 0.79 | 0.021 |
| White blood cell count (×109/L) | 7.90 (6.20, 10.20) | 7.60 (5.35, 8.55) | 0.115 |
| Total serum protein (g/L, x ±s) | 70.02 ± 6.89 | 68.46 ± 8.38 | 0.275 |
| Albumin (g/L) | 39.50 (36.00,42.90) | 33.90 (30.80, 38.55 ) | <0.0001 |
| Total cholesterol (mmol/L) | 4.58 (3.88, 5.37) | 3.92 (3.43, 5.37) | 0.150 |
| Triglyceride (mmol/L) | 1.23 (0.85, 1.83) | 1.31 (0.73, 1.69) | 0.699 |
| LDL-C (mmol/L) | 2.64 (2.04, 3.29 ) | 2.34 (1.93, 3.42 ) | 0.323 |
| HDL-C (mmol/L) | 1.00 (0.79, 1.24 ) | 0.94 (0.76, 1.06 ) | 0.233 |
| Uric acid (µmol/L) | 347.50 (268.00, 432.00) | 357.00 (289.8, 465.00) | 0.362 |
| Glucose (mmol/L) | 5.80 (5.00, 7.10) | 5.40 (4.70, 6.60) | 0.268 |
| NLR | 2.42 (1.77,3.51) | 3.42 (1.87,5.81) | 0.028 |
| PLR | 113.15 (84.24,150.83) | 148.72 (111.51,304.22) | 0.0006 |
Notes.
Abbreviations
- CA-AKI
- contrast-associated acute kidney injury
- eGFR
- estimated glomerular filtration rate
- ACEI/ARB
- angiotensin-converting enzyme inhibitor/angiotensin receptor blocker
- LDL-C
- high-density lipoprotein cholesterol
- HDL-C
- low-density lipoprotein cholesterol
- NLR
- neutrophil to lymphocyte ratio
- PLR
- platelet to lymphocyte ratio