Table 2.
Characteristics and echocardiography measurements of mice after 4 weeks Ang II infusion
| Groups | Control | BMS309403 | Ang II | Ang II+BMS309403 |
|---|---|---|---|---|
| BW (g) | 23.31±1.32 | 23.30±1.36 | 23.85±1.02 | 23.18±1.62 |
| HR (bpm) | 452.63±35.40 | 450.38±30.90 | 442.38±25.85 | 464.25±31.48 |
| LV mass (mg) | 75.65±4.62 | 76.74±5.93 | 99.47±6.63*** | 86.43±5.74### |
| LVIDd (mm) | 3.54±0.31 | 3.58±0.19 | 4.02±0.21** | 3.67±0.22## |
| LVIDs (mm) | 2.47±0.19 | 2.57±0.11 | 3.05±0.36** | 2.66±0.25# |
| CO (mL/min) | 14.60±1.67 | 15.77±1.87 | 18.11±1.85** | 15.51±2.23# |
Data are represented as means±SD
**P<0.01, *** P<0.001 vs control group; #P<0.01, ##P<0.01, ###P<0.001 vs Ang II group
BW: Body weight; HR: Heart rate; LV mass: Left ventricle mass; LVIDd: Left ventricular internal diameter (diastole); LVIDs: Left ventricular internal diameter (systole); CO: Cardiac output