Figure 2.

Evaluation of the subchondral bone by using micro-CT. (A) Sagittal image of the medial tibial plateau of the sham group; (B) Bone loss, loose microstructure, and a defect zone were shown in the subchondral bone (white arrow) in the osteoporotic osteoarthritis (OP OA) group; (C) Increased bone mass and improved microstructure were shown in the equol (EQ) group (vs the OP OA group); (D-H) Analysis result of the microstructural parameters including bone mineral density (BMD), bone volume fraction (BV/TV), trabecular number (Tb.N), structure model index (SMI), and trabecular spacing (Tb.Sp). #P<0.05 vs the OP OA group; @P<0.05 vs the sham group