Table 2.

Determination of At-Risk Patients. Because we acknowledged that our estimate of the incidence of tetracycline-induced pseudotumor cerebri syndrome (PTC-T) was an overestimate, we estimated the number of at-risk patients in the state of Utah.

	Population served by University of Utah Health system	Utah Population
Total Population (all ages)	2,547,636 (8-year total) in the FURTHeR database	2,922,072 from the U.S. Census Bureau 2,922,072 × 8 study years = 23,376,576 (8-year total)
Population age 12–50	876,358 (8-year total) in the FURTHeR database (34.4% of patients in the database)	23,376,575 × 34.4% = 8,041,278 (estimated 8-year total)
Ages 12–50 years and prescribed a tetracycline	960 (8-year total) in the FURTHeR database (0.11% of the patients in the database ages 12–50 years)	8,041,278 × 0.11% = 8,809 (8-year total)
Ages 12–50 with PTCS	274 (8-year total)	274 (8-year total)
Ages 12–50 with PTC-T	45 (8-year total)	45 (8-year total)

FURTHeR = Federated Utah Research and Translational Health e-Repository; PTCS = pseudotumor cerebri syndrome. Percentages have been rounded for simplicity.