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. 2022 Apr 27;71(12):2913–2928. doi: 10.1007/s00262-022-03202-8

Fig. 3.

Fig. 3

Patient #5, clinical course a Timeline demonstrating initial diagnosis, status of remission and therapeutic interventions. b Leukocytes, thrombocytes and hemoglobin values during clinical course. c Frequencies of blasts, NPM1 and WT1 NCN in bone marrow during clinical course. NPM1 NCN at day + 665 and + 819 were measured from peripheral blood. d Gene mutations at initial diagnosis of AML measured by next-generation-sequencing (54-myeloid-gene panel)