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. 2022 May 28;71(12):3057–3070. doi: 10.1007/s00262-022-03223-3

Table 1.

The risk factors for lymph node metastasis (LNM) in the enrolled gastric cancer patients

Factors No LNM (%) χ2 P Model fitting criteria Likelihood ration tests
N0 N1 N2 N3  − 2 log likelihood χ2 df P
Age (years) 9.099 0.028 288.709 4.440 3 0.218
 < 60 48 20 (41.7) 4 (8.3) 5 (10.4) 19 (39.6)
 ≥ 60 98 33 (33.7) 14 (14.3) 28 (28.6) 23 (23.5)
Gender 0.878 0.831 / / / /
Male 101 38 (37.6) 12 (11.9) 24 (23.8) 27 (26.7)
Female 45 15 (33.3) 6 (13.3) 9 (20.0) 15 (33.3)
Lauren classification 27.076 0.000 303.535 19.266 6 0.004
Intestinal 54 29 (53.7) 8 (14.8) 12 (22.2) 5 (9.3)
Diffuse 24 11 (45.8) 0 (0.0) 3 (12.5) 10 (41.7)
Mixed 68 13 (19.1) 10 (14.7) 18 (26.5) 27 (39.7)
Depth of tumor invasion 51.574 0.000 325.129 40.860 9 0.000
T1 36 26 (72.2) 5 (13.9) 2 (5.6) 3 (8.3)
T2 19 10 (52.6) 2 (10.5) 5 (26.3) 2 (10.5)
T3 67 16 (23.9) 10 (14.9) 20 (29.9) 21 (31.3)
T4 24 1 (4.2) 1 (4.2) 6 (25.0) 16 (66.7)
Untreated sIL-8 level 11.606 0.009 304.242 19.973 3 0.000
 ≤ 62 pg/ml 68 23 (33.8) 15 (22.1) 12 (17.6) 18 (26.5)
 > 62 pg/ml 78 30 (38.5) 3 (3.8) 21 (26.9) 24 (30.8)

sIL-8 serum IL-8