TABLE 4.

Efficiency of monoclonal antibodies^a

Virus	Yr	No. of IFA tests found to be:				SENS (%)	SPEC (%)	PPV (%)	NPV (%)
		TP	FN	FP	TN
RSV	87–89b	77	12	52	304	86.5	85.4	60.0	96.4
	89–90	82	6	109	526	95.3	82.8	42.9	98.9
	90–91	89	6	62	523	93.7	89.4	58.9	98.9
	91–92	176	23	71	777	88.4	91.6	71.3	97.1
	92–93	26	1	5	685	96.3	99.3	83.9	99.9
	93–94	111	9	54	748	92.5	93.3	67.3	98.8
	94–95	55	8	15	617	87.3	97.6	78.6	98.7
	95–96	109	10	33	540	91.6	94.2	76.8	98.2
	96–97	18	2	1	901	90.0	99.9	94.7	99.8
	Total	743	77	402	5,621	90.6	93.3	64.9	98.7
INFA	87–89	13	0	3	304	100	99.0	81.3	100
	89–90	32	2	47	526	94.1	91.2	40.5	99.6
	90–91	7	13	0	523	35.0	100	100	97.6
	91–92	90	5	17	777	94.7	97.9	84.1	99.4
	92–93	17	7	2	685	70.1	97.4	89.5	99.0
	93–94	120	15	66	748	88.9	91.9	64.5	98.0
	94–95	25	0	16	617	100	97.5	61.0	100
	95–96	49	32	10	540	60.5	98.2	83.1	94.4
	96–97	134	17	127	901	88.7	87.8	51.3	98.2
	Total	487	91	288	5,621	84.3	95.1	62.8	98.4
INFB	87–89	5	4	14	304	55.6	95.6	26.3	98.7
	89–90	0	0	0	526
	90–91	52	7	16	523	88.1	97.0	76.5	98.7
	91–92	0	0	0	777
	92–93	132	27	18	685	83.0	97.4	88.0	96.3
	93–94	0	0	0	748
	94–95	0	0	0	617
	95–96	26	7	8	540	78.8	98.5	76.5	98.7
	96–97	17	4	1	901	80.9	99.9	94.4	99.6
	Total	232	49	57	5,621	82.6	99.0	80.5	99.1
PIV1	87–89	1	0	0	319	100	100	100	100
	89–90	23	1	0	526	95.8	100	100	99.9
	90–91	2	0	0	523	100	100	100	100
	91–92	16	9	7	777	64.0	99.1	69.6	98.9
	92–93	0	0	0	685
	93–94	21	7	2	748	75.0	99.7	91.3	99.1
	94–95	0	0	0	617
	95–96	28	2	1	540	93.3	98.5	96.6	99.6
	96–97	0	0	0	901
	Total	91	19	10	5,621	82.0	99.8	89.2	99.7
PIV2	87–89	0	0	0	304
	89–90	0	0	0	526
	90–91	4	2	0	523	66.7	100	100	99.6
	91–92	4	2	0	777	66.7	100	100	99.7
	92–93	1	13	0	685	7.1	100	100	98.1
	93–94	0	0	1	748	100	99.9	100	99.9
	94–95	4	6	0	617	40.0	100	100	99.0
	95–96	1	0	0	540	100	100	100	100
	96–97	5	4	1	901	55.6	99.9	83.3	99.6
	Total	19	27	2	5,621	41.3	99.9	90.5	99.8
PIV3	87–89	9	3	3	304	75.0	99.0	75.0	99.0
	89–90	13	2	7	526	86.7	98.7	65.0	99.6
	90–91	48	6	3	523	88.5	99.4	94.1	98.9
	91–92	18	4	0	777	81.8	100	100	99.5
	92–93	35	5	4	685	87.5	99.4	89.7	99.3
	93–94	15	4	2	748	78.9	99.7	88.2	99.5
	94–95	24	3	3	617	88.9	99.5	88.9	99.5
	95–96	19	3	1	540	86.4	99.8	95.0	99.5
	96–97	34	2	2	901	94.4	99.8	94.4	99.8
	Total	215	32	25	5,621	87.0	99.6	89.6	99.4
ADENO	87–89	3	5	0	304	37.5	100	100	98.4
	89–90	18	6	0	526	75.0	100	100	98.9
	90–91	26	11	0	523	70.3	100	100	97.9
	91–92	7	8	1	777	46.7	99.9	87.5	99.0
	92–93	13	7	1	685	65.0	99.8	92.9	99.0
	93–94	10	6	1	748	62.5	99.9	90.9	99.2
	94–95	22	9	0	617	71.0	100	100	98.6
	95–96	10	7	1	540	58.8	98.5	90.9	98.7
	96–97	7	4	0	901	63.6	100	100	99.6
	Total	116	63	4	5,621	64.8	99.9	96.7	98.9
	Overall	1,903	358	788	5,621	84.2	87.7	70.7	94.0

^aValues in boldface are averages rather than totals. 

^bYears were combined because of low numbers.