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. Author manuscript; available in PMC: 2023 Nov 1.
Published in final edited form as: Osteoarthritis Cartilage. 2022 Aug 24;30(11):1468–1481. doi: 10.1016/j.joca.2022.08.008

Figure 5.

Figure 5.

GFS normalizes the reduced mechanical stimulation threshold for firing in MIA-OA animals. (A) Preparation design for recording from the L4 dorsal root during application of von Frey filaments to the RF in the plantar skin. (B) Effect of 120s-20Hz GFS on the mechanical threshold for firing. *** P<0.001 by 2-way repeated measure ANOVA followed by Sidak’s post hoc test. (C) Effect size of GFS in MIA-OA and control animals. *** P<0.001 by t-test. Data are from n=5 rats with saline injection and n=5 rats with injection of MIA.