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. Author manuscript; available in PMC: 2023 Apr 14.
Published in final edited form as: Clin Cancer Res. 2022 Oct 14;28(20):4410–4424. doi: 10.1158/1078-0432.CCR-21-4148

Table 1.

Breast cancer cohorts explored in this study: anthracycline-based neoadjuvant chemotherapy (BRCA-ACT) for HER2-negative patients and targeted therapy for HER2+ breast cancers (BRCA-TCHP).

BRCA-ACT BRCA-TCHP
N 242 129
Pathologic response
Responder 66 66
Non-responder 176 63
Recurrence-free Survival
Event observed, N [median time-to-event, months] 48 [25.0] N/A
Censored, N [median time-to-last-followup, months] 109 [53.3] N/A
Unavailable 85 129
HER2 status
Positive, N 0 129
Negative, N 242 0
Hormone Receptor status
Positive, N 152 86
Negative, N 90 43
Age, years 49.6 ± 10.5 50.1 ± 11.1
Longest diameter, mm 5.4 ± 2.9 4.4 ± 2.9
Cohort
Training 98 69
Testing 144 60