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. Author manuscript; available in PMC: 2023 Aug 23.
Published in final edited form as: Crit Rev Biochem Mol Biol. 2022 Aug 23;57(4):399–411. doi: 10.1080/10409238.2022.2113030

Figure 4: Cross-β fibrils can be made of one or multiple protofilaments.

Figure 4:

A) View down the fibril axis (Top) and along the fibril axis (Side) of an idealized cross-β core formed by a single (proto)filament. In such a fibril there is only one monomer per layer. B) Idealized cross-β fibril that is made of two protofilaments. The top view shows nicely how this fibil has two identical monomers per layer.