Table 2.

Apparent pK_D values^a of DKFZ-748 and reference compounds by chemical proteomics profiling.

^aDetermined by LC-MS/MS after dose-dependent competition pulldown assay from three or two^b separate experiments, each performed with eleven dose levels. For structure of CHDI00465983 and dose-response curves with individual datapoints, see Figure S2. Apparent pK_D values with standard deviations are listed in Table S6.