Table 1.

Optimization of Reaction Conditions

entry	reagent	solvent	T[°C]	time [h]	yield[%]b
1	2a	CHCl3	70	6	0c
2	2b	CHCl3	70	6	14
3	2b	CHCl3	90	6	45
4	2b	CHCl3	90	12	70
5	2b	PhCH3	90	12	27
6	2b	PhCF3	90	12	50
7	2b	CH3CN	90	12	13
8	2b	DCE	90	12	73 (68)d
9	2b e	DCE	90	12	68
10	2c	DCE	90	12	41
11	2d	DCE	90	12	14
12	2b f	DCE	90	12	39

^aConditions: 0.1 mmol 1i, 0.1 mmol 2, 0.5 mL solvent (0.2 M).

^bYield determined by ¹H NMR using 1,1,2,2-tetrachloroethane as the internal standard.

^cNo reaction.

^dIsolated yield from 0.2 mmol scale reaction.

^eUsing 2b stored in the desiccator for 1 month and DCE stored on the benchtop.

^f0.02 mmol (20 mol %) 2b used.