Table 2.
Age-adjusted univariate analysis of individual and neighborhood-level factors and lung cancer incidence among 37,650 never-smokers in the Black Women’s Health Study.
| Factor | NSCLC cases (N) |
Age-adjusted sHR (95 % CI) |
|---|---|---|
| Age at enrollment | 77 | NA |
| Body mass index | 77 | 0.99 (0.96, 1.03) |
| PM2.5, ug/m3 (continuous) | 77 | 1.01 (0.95, 1.08) |
| Educational attainment | ||
| High school degree or less | 20 | 1.05 (0.61, 1.81) |
| Some college | 33 | 1.02 (0.61, 1.69) |
| College degree and above | 24 | Reference |
| p-value (test of homogeneity) | 0.98 | |
| Annual family income ($) | ||
| <25,000 | 14 | 0.49 (0.21, 1.23) |
| 25,000–50,000 | 25 | 0.58 (0.29, 1.54) |
| 50,000–100,000 | 24 | 0.64 (0.33, 1.25) |
| >100,0000 | 14 | Reference |
| p-value (test of homogeneity) | 0.36 | |
| Health insurance status | ||
| No | 4 | 1.40 (0.52, 3.75) |
| Yes | 73 | Reference |
| Secondhand smoke at home | ||
| No | 17 | Reference |
| Yes | 60 | 1.29 (0.74, 2.26) |
| Secondhand smoke at work | ||
| No | 26 | Reference |
| Yes | 51 | 1.93 (1.21, 3.08)* |
| Neighborhood Concentrated Disadvantage Index per 10 unit increase | 77 | 1.30 (1.03, 1.63)* |
| Neighborhood SES Index per 10 unit increase | 77 | 0.82 (0.63, 1.07) |
*
p-value < 0.05.
CI: confidence interval; NA: not applicable; NSCLC: non-small cell lung cancer; PM2.5: particulate matter <2.5 μm in diameter sHR: subdisribution hazard ratio. Test of homogeneity compares the equality of estimates across the categories within a variable.