Table 3.

Risk indicators for MRONJ according to logistic regression analysis.

Explanatory variable	Odds ratio	[95% CI]	P value
Tooth extraction (no; 0, yes; 1)	0.53	[0.1220–2.270]	0.390
Total administration period (≤48 months; 0, ≥49 months; 1)	2.33	[0.5390–10.100]	0.258
Drug holiday (≥3 months; 0, ≤2 months; 1)	1.21	[0.2990–4.930]	0.786
Route of administration (oral; 0, injection; 1)	5.01	[1.1100–22.600]	0.036 ∗
Antiresorptive agent (BPs; 0, Dmab; 1)	2.29	[0.4000–13.100]	0.352

BP, bisphosphonate; Dmab, denosumab; CI, confidence interval.

∗P < 0.05.