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. Author manuscript; available in PMC: 2023 Oct 20.
Published in final edited form as: Cell Chem Biol. 2022 Oct 6;29(10):1517–1531.e7. doi: 10.1016/j.chembiol.2022.09.002

Figure 1. TERT inhibitor NU-1 modulates cancer cell gene expression.

Figure 1

(A) Chemical structures of TERT inhibitors chrolactomycin and NU-1 and the inactive des-exomethylene analog NU-2.

(B-C) Enrichment of downregulated (B) and upregulated (C) pathways in NU-1 treated MCF7 cells through Reactome Gene Ontology (GO) analysis. Dots, number of DEGs. Bars, −Log10(p-value) for each enriched pathway.

See also Figure S1.